Percutaneous osteoplasty combined with multiholed catheter bone cement injection for metastatic tumor-induced impending fracture of the long bone

doi:10.3969/j.issn.2095-4344.0948

Abstract

Abstract:

BACKGROUND: The long bone is the recurrent site of metastatic tumors. Broken sclerotin weakens the support strength of long bone, which leads to fracture under external force. Percutaneous osteoplasty can reinforce local bone strength and kill tumor cells. But it cannot fortify the whole long bone enough to avoid fracture occurrence.

OBJECTIVE: To compare the efficacy of percutaneous long bone cementoloplasty with and without embedding a cement-filled catheter in the medullary canal for painful long bone metastases with impending fracture.

METHODS: Forty-two patients were divided into two groups according to the treatment schedule. Patients in control group were treated with percutaneous osteoplasty combined with bone cement injection and the other patients in experimental group were treated with percutaneous osteoplasty combined with multiholed catheter bone cement injection. Rate of bone cement leakage was statistically analyzed. Visual analogue scale score, Karnofsky function score and number of cases of long bone fracture were detected and compared between the two groups.

RESULTS AND CONCLUSION: (1) All the patients completed puncture and bone cement injection. There were seven cases of bone cement leakage in the control group and eight cases of bone cement leakage in the experimental group, and no difference existed in two groups (P > 0.05). (2) The visual analogue scale score and Karnofsky function score in each patient were both improved after treatment (P < 0.05), but there was no difference between the two groups (P > 0.05). (3) Five cases of bone re-fracture were found in the control group, but no case in the experimental group. To conclude, the use of percutaneous osteoplasty combined with multiholed catheter bone cement injection for metastatic tumor-induced impending fracture of the long bone can prevent bone fracture at the lesion site.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Key words: Fractures, Bone, Fractures, Spontaneous, Neoplasm Metastasis, Tissue Engineering

CLC Number:

R318

Ye Yong, Liu Xunwei, Wang Zhiguo, Li Zunyong, Xie Zhiyong, Sun Gang. Percutaneous osteoplasty combined with multiholed catheter bone cement injection for metastatic tumor-induced impending fracture of the long bone[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(34): 5413-5418.

Figures/Tables 5

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